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What are “Tablet Coating – Defects”?

Posted on July 3, 2014 By Frndzzz

List of  some tablet coating defects which may affect the tablet formulation and bioavailability of drug are as follows.

(1) Picking and Sticking,

(2) Color variation,

(3) Orange peel effect,

(4) Twinning,

(5) Capping and lamination,

(6) Mottled color,

(7) Roughness,

(8) Hazing or Dull film

(9) Bridging,

(10) Erosion,

(11) Filling,

(12) Chipping,

(13) Blistering,

(14) Cracking,

(15)  Peeling and frosting.

These are some of common defectes observed during formulation of tablets.

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