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Tablet coating: "Orange Peel Defect"

During tablet coating Orange peel defect is observed due to inadequate spraying or spreading of the coating solution.

Before the drying this coating solution causes bumpy or orange peel effect on the coating.

It is caused due to high spray rate and high pressure.

This defect can be prevented by thinning of the polymer solution and adding additional solvents.

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Tablet Coating: color variation Defects

During Tablet coating , color variation defect is observed sometimes.

 This defect is caused by improper mixing on the tablets, or by insufficient coating and also caused by uneven spray pattern on tablets.

 After coating the migration of soluble dyes or any additives during drying may give tablet a spotted and mottled apperation.

Due to this defect color variation is observed.

What are "Tablet Coating - Defects"?

List of  some tablet coating defects which may affect the tablet formulation and bioavailability of drug are as follows.

(1) Picking and Sticking,

(2) Color variation,

(3) Orange peel effect,

(4) Twinning,

(5) Capping and lamination,

(6) Mottled color,

(7) Roughness,

(8) Hazing or Dull film

(9) Bridging,

(10) Erosion,

(11) Filling,

(12) Chipping,

(13) Blistering,

(14) Cracking,

(15)  Peeling and frosting.

68 Applications of Nanotechnology - Overview of the applications of Nanotechnology

There are various applications of nanotechnology which we are going to discuss below. Nanotechnology provides various benefits in this world of technology. Smaller as well as cheaper, lighter, faster and clever things , which consume less raw materials and less energy can be prepared with the help of nanotechnology. It also offers various opportunities in creating various functions and new features. A team effort is required in creating any new feature with the help of nanotechnology

 

Polymers applications in everyday life

Polymers have many applications in various fields as well as in everday life.

Let us check it out some uses of polymers.

 Polymers are used in clothing, oil recovery, food and flavours, agriculture, packaging, consumer items like clothing, toys, skin care

Polymers also used in automative parts, pipes, parts, additives etc.

Also used in electronics as well as in medicines such as in formulation of proteins, antibiotics, gel caps or in coating of tablets. 

Disadvantages & Advantages of an TLC

Some Disadvantages & Advantages of an TLC.

In Thin layer Chromatography also called (TLC) is widely used method for the separation and detection of an molecule from a given mixture of compounds.

This method is used for the separation of non volatile compounds.

This is generally performed on the thin sheet of aluminum or thin sheet of glass or plastic.

This sheet are coated with different media, commonly used are silica gel, cellulose etc.

The sample is applied on this plate and it is called stationary phase.

How to Choose Watermelon Varieties

While most of us can remember enjoying watermelons in the summertime as far back as childhood, it may be surprising to find out that today there are around two hundred different watermelon varieties grown. The traditional oblong green watermelon with pink flesh and black seeds is no longer the only choice. Today there are seedless varieties as well as the traditional watermelons with seeds.

What is Crown lengthening procedure?

Let us check out what is Crown lengthening procedure to know more about dental care? If you have gummy smile and you feel bad about that.  Here is one solution for your problem, procedure called “Crown Lengthening Procedure”.  The cost for this treatment varies. This medical procedure is executed by the dental professionals to help Gummy smile people. In this procedure dental professionals reshape your excessive gum and bone tissue to expose your natural teeth and improve your smile.

Medicinal Uses of Aloe Vera in Points

Check out Medicinal Uses of Aloe Vera in Points which are discussed below. So let us find out some points on Medicinal uses to know more about Aloe vera.

Medicinal uses of aloe vera are :

Aloe vera helps to reduce high blood pressure and also lowers high cholesterol.

It helps to protect the body from stress and prevents kidney stones.

Aloe Vera supports immune system and also stabilizes blood sugar level.

Aloe vera helps in cooling and repairing sunburn skin and it also hydrates the skin.

Process Validation

Process validation: It can be defined as the documented evidence which provides a high degree of assurance that the process which is going to be performed will consistently produce a product , meeting its pre determined specifications and all the quality attributes.

Process Validation is classified into four types which are as follows:

Prospective Validation

Retrospective Validation

Concurrent Validation

Revalidation

Process Validation is divided into three stages which are  as follows:

Process Design - Stage I

Advantages and disadvantages of Debentures

Check out Advantages and Disadvantages of Debentures discussed below. So let us find out some information  to know more about it. The debentures which are generally issued by the corporations, are promises to pay specific amount of principal or money at a specified time or date over the particular course of the loan tenure, during which time interest is paid at a fixed rate on decided dates.

Advantages of Debentures :

Debentures is used to provide long terms funds to the company when needed.

All About the Square Watermelon

Everyone loves to eat watermelon in the summer, but its round, oblong shape makes it hard to carry, hard to slice, and hard to store but now there’s a solution the square watermelon. Developed by a farmer in Japan almost twenty years ago, the square watermelon can now be purchased throughout Japan.

Still, most of the people in the world have never seen or eaten a square watermelon. In Japan, they are only purchased by the wealthy.